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Author: Kussin Clarissa

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The Weakest Leak :

Autoimmunity and Leaky Gut Explained

They say that any system is only as strong as its weakest link. It turns out, our digestive and immune systems are only as strong as their weakest leak.

Imagine your gut as the body’s security guard. The tight junctions between the cells of your intestines decide who gets in and who doesn’t. But what happens when the gut becomes too permissive and allows unwanted guests through? That’s where “leaky gut” comes into play.

Leaky gut, or intestinal permeability, is a condition where the lining of the intestines becomes more porous than it should be. Instead of acting like a strict bouncer to the coolest club in town, the tissue starts allowing substances that shouldn’t enter your bloodstream. This includes undigested food particles, bacteria, and toxins.

When the gut barrier is compromised and unwanted intruders enter the bloodstream, your immune system, which usually only targets harmful invaders, can get confused and launch a response against your body’s own tissues instead.

It’s like friendly fire within your body! According to the NIH (National Institutes of Health) around 23.5 million (7%) Americans suffer from an autoimmune condition. And 75% of those affected are women.

Hashimoto’s thyroid disease, ulcerative colitis, rheumatoid arthritis, psoriasis, vitiligo and multiple sclerosis are some of the more than 80 known autoimmune diseases commonly seen at Carolina Total Wellness.

Three Steps to Preventing or Reversing Autoimmune Disease:
Not every autoimmune disease is curable or reversible but there are some proven steps you can take to reduce the effects on your health.

1. Manage Your Stress Stress isn’t just in your mind; it affects your gut, too. When we are facing a perceived physical or emotional threat, our bodies are wired to respond by directing resources to your vital organs and away from your digestive and reproductive functions. When you don’t have sufficient digestive enzymes and gastric acid to break foods down, they may be more irritating to your gut lining and/or penetrate the lining as larger particles than your blood stream knows how to handle. It’s not always possible to avoid stress but you can practice strategies to help you minimize the effects. Get 8 consistent hours of sleep each night. Practice saying ‘no’ – it is a full sentence. Go outside and take a walk – without devices. Laugh with a good friend.

2. Eat Gut-Healing Foods Eating a balanced diet is crucial for maintaining gut health. A diet rich in fiber, fruits, and vegetables promotes a diverse gut microbiome and a healthier gut lining. Use the rainbow as a template to guide your shopping list and eat foodsof every color several times per week. Probiotics, found in foods like yogurt, sauerkraut and kimchi help eliminate toxins and aid the digestion of nutrients from the foods you eat. Eat fermented foods several times each week to strengthen the lining of your digestive tract. Bone broth has proteins and gelatin to soothe the inner lining of the gut. Sip on some bone broth instead of coffee in the morning if you’re trying to kick the caffeine habit.

3. Fasting Fridays Once a week, skip breakfast (and the coffee/creamer.) An occasional, extended break from the hard work of digestion, also known as intermittent fasting, lets your gut clean out old debris and calms the immune system. You may discover improved mental clarity and energy, too. In fact, you may like it so much that you decide to skip breakfast two or three days a week. Healing the Gut.

If you suspect you have a leaky gut or an autoimmune disease, consult afunctional medicine practitioner. They can recommend personalized approaches like dietary changes, supplementation, and lifestyle modifications to heal your gut and reduce inflammation.

Autoimmunity and leaky gut are two puzzle pieces that fit together more than we once thought. Maintaining a healthy gut through a balanced diet, managing stress, and seeking professional guidance when needed can be your key to preventing or managing autoimmune diseases.

Remember, the journey to optimal health is unique for everyone. Keep exploring, learning, and making choices that support your well-being.  

Your Partner In Health,
Erica Nelson, MSPH, NBC-HWC
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Foods for Menopause and Perimenopause

The hormonal shifts that accompany perimenopause and menopause lack a clear instruction manual, often leaving many women in a continuous cycle of trial and error when it comes to managing their symptoms. Fortunately, one of the most potent tools available for regaining control of your hormones is the food you consume. Certain foods contribute to hormone balance and can help alleviate perimenopause and menopause symptoms, while others can disrupt your body’s hormonal equilibrium.

When essential nutritional elements are lacking, hormonal imbalances can arise, leading to mood swings, weight gain, hot flashes, and reduced libido. The primary hormones affected during perimenopause and menopause are estrogen, progesterone, insulin, and testosterone, and your dietary choices can significantly impact these hormones. For instance, excessive sugar consumption can elevate insulin levels, trigger inflammation, and exacerbate nearly every perimenopausal symptom. On the other hand, incorporating vegetables, fruits, nuts, and seeds into your diet can provide phytonutrients and healthy fats that aid in managing even the most challenging menopause symptoms.

While there’s no one-size-fits-all diet, several foods have proven beneficial for most people seeking to balance their hormones:

1. Brassica (aka cruciferous) Vegetables: These include broccoli, cauliflower, kale, and cabbage, which contain indole-3-carbinol—a compound that helps metabolize estrogen in the gut and liver. This can be particularly helpful in addressing estrogen dominance.

2. Healthy Fats: Avocados, nuts, seeds, and fish are rich inomega-3 fatty acids and other fats crucial for reducing inflammation and supporting hormone production, especially progesterone.

3. Fiber-Rich Foods: Fiber is essential for gut health, which plays a critical role in hormone balance. Low-starch fruits and veggies, nuts, seeds, and whole grains can boost your fiber intake, aiding in estrogen metabolism and blood sugar regulation.

However, there are also foods and drinks that should be limited or avoided:

1. Caffeine: Excess caffeine can lead to increased stress hormone production and elevated cortisol levels, potentially exacerbating fatigue and estrogen levels.

2. Processed Carbs and Sugar: As tolerance to sugar decreases with age, limiting simple carbohydrates and sugars (like table sugar, baked goods, and packaged foods) becomes crucial for managing blood sugar and insulin levels.

3. Alcohol: Even moderate alcohol consumption can disrupt hormones, affect brain aging, and lead to elevated insulin levels and estrogen dominance.

4. Gluten: Gluten sensitivity can contribute to gut issues, thyroid problems, and autoimmune conditions, making it advisable to assess its impact on your health

Balancing your diet can ease the transition into perimenopause and menopause, regardless of whether you’re just beginning to experience symptoms or are already in the midst of them. By making thoughtful dietary choices, you can navigate this phase of life with greater vitality and well-being.

Your Partner In Health,

Sara Yadlowsky, FMHC

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Concussion Care 2023

Frances Meredith, MD

Concussion is so much more common than we realize, a frequent occurrence in kids and teens, especially athletes, and increasing frequency in the elderly and unstable of gait.  The fact that memory loss can be associated creates a scenario where concussions are simply not recalled, but can lead to long lasting symptoms and deterioration in quality of life.   Most people do not seek care, and when they do, they are usually given out dated advice unless seen at a dedicated concussion center or provider. Sadly, most medical professionals, even in an urgent care or ER, are not trained in current cutting edge acute concussion care. Concussion centers have only come into existence since 2000, and active research has been lacking until recently.

What is very clear is that with any symptoms suggestive of concussion (including loss of consciousness, dizziness, or feeling “detached”, vision changes, headache, nausea), physical activity must stop immediately. Theon field symptom that best predicts a longer recovery is dizziness followed by “fogginess”. Estimates according to Dr Michael Collins, head of the concussion center at UPMC University of Pittsburgh Medical Center, are that for every minute a player is back on the field, his/her recovery time is lengthened by7-8 days (1). The average recovery time for a mild concussion is 18 days, with15 minutes back on the field prolonging this to 44 days.  What is not widely recognized is that immediate evaluation, a graded exercise and brain rehab plan, and supplement support can greatly speed recovery.   
           
EVALUATION

An evaluation by a doctor familiar with concussion is essential after head trauma. Assuming the doctor feels you can be monitored at home, someone should stay with you and check on you for at least 24 hours to make sure symptoms are not worsening. This should be followed be evaluation by a true concussion expert as soon as possible. Evaluation should include an assessment of the mechanism of injury itself(video very helpful if available), vestibular ocular motor screening, balance and autonomic nervous system testing, and can include more sophisticated testing including a qEEG brain scan and Right Eye testing. An assessment of preconcussion risk factors which might delay recovery is important as well as a determination of the type of concussion. There are, according to current research, six types of concussion: cognitive fatigue, vestibular, ocular, migraine, anxiety, and neck based. These can overlap, and these different types are treated with different therapeutic modalities guided by testing.

MANAGEMENT

Mental rest and eye rest are essential in the early days after concussion. How long you’ll need to rest your brain and body will depend on the severity of your concussion and rapidity of resolution of symptoms. Your concussion specialist will help you to create a plan to allow the brain to heal. This will include lots of rest, optimizing hydration, and initially completely avoiding activities requiring mental concentration including homework, watching TV, playing video games, texting and using computers. These activities should be avoided for at least the first 48 hours after concussion, then gradually brought back incrementally as tolerated. Physical activity should also be limited in the first few days to mild activity such as walking that does not trigger symptoms. At that time exercise becomes essential in the healing process. Previously recommended complete bedrest, in darkness avoiding all stimuli, is no longer recommended.  A structured, gradually progressing exercise plan should be created with your concussion specialist. Exercise programs after concussion often consist of 45-90 min daily of intense activity to increase blood flow to brain. Exercise is the best way to increase Brain Derived Neurotrophic Factor (BDNF), essential in neuroplasticity and brain healing.  Optimal sleep is essential, with experts recommending at least 8 hours nightly with consistent bedtime and awakening times, taking only short naps when needed during the day in order to ensure optimal nighttime sleep. Your doctor may recommend, as screentime and mentally focused activities are reintroduced, a lightened work/school schedule, and spacing out screentime such as homework in short blocks. Your doctor will likely recommend other modalities to “rebab” the brain including a combination of exercises for vision and balance, Neurofeedback, autonomic nervous system retraining, and laser therapy. Often chiropractic care will be advised to reestablish alignment in the neck as misalignment in the neck gives the brain incorrect information about where you are in space.  For pain relief discuss with your doctor whether Tylenol is right for you as NSAIDS such as Ibuprofen or Aspirin can increase risk of bleeding and actually prolong inflammation. As the brain is working hard to clear out damage, it is essential to abstain from other toxins to the brain such as alcohol, and lay off cigarettes if you smoke.

   “Energy Crisis”

Optimal nutrient support at the onset of concussion may have an impact on speed of recovery.  To understand why, it is key to understand what is happening in the brain in the minutes after concussion. The brain depends on glucose for energy.

Following concussion, an “energetic crisis” occurs in the first 24 hours after injury where the brain can no longer easily metabolize glucose. Just when the brain needs more energy to heal, it has much less. This is followed by neuroinflammation at the site of injury that can further impair metabolism and energy production in the brain. Neuronal damage is also accompanied by vascular damage in which the pumps that keep nerves stable begin to fail. Then glutamate, a neurotransmitter toxic when in high amounts, can leak out and create inflammation and cell death. The goal is to decrease energetic demands on the brain and provide an alternate source of fuel other than glucose: ketones. Ketones serve as an alternate fuel source for the brain, typically created from fat stores while fasting. There is limited research in this area but animal studies are supportive and human studies are ongoing.  The mechanisms of injury above guide treatment options that can be helpful in the hours to days after concussion. These can include:

 –Ketogenic diet: Ketones created in a low carbohydrate “ketogenic diet” support brain energy and can be supported by “exogenous ketones” in powder form.  Studies in rodents show therapeutic benefit(4,5); studies in humans are lacking and ongoing but safety of ketogenic diet has been established.

–Anti-inflammatory nutrients and anti-inflammatory diet:  Nutrients such as fish oil, DHA, Vitamin D,NAC, Vit C, and curcumin have growing research to support their therapeutic benefit.

–Phospholipid Support: Phospholipids, the main component of cell membranes, are made up of fats and phosphate. Studies suggest phospholipid support can help repair a damaged blood brain barrier and reduce tissue damage with traumatic brain injury (TBI)(8,9)

–Hyperbaric oxygen treatment: Research suggests hyperbaric oxygen may be beneficial in both acute and chronic concussion or CTE (chronic traumatic encephalopathy) (6,7) however more research is needed.
 
As the research grows, our approach to concussion will be fine tuned in the years to come.

Please spread this information to family and friends as this knowledge can be the difference between return to play with speedy recovery and a lifetime of frustrating neurologic and psychologic symptoms that can be the result of poorly managed concussion. With expert management, top practitioners in the field firmly believe that complete healing is possible.

Your Partner In Health,
Frances T. Meredith, MD
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Prevention and Treatment of Viral Infections

(Including Covid, Flu, RSV and the common cold)

The providers at Carolina Total Wellness recommend the following lifestyle and supplement supports to optimize immune function, decrease viral transmission, reduce viral activity and support the body’s immune response to common viral infections.

Lifestyle:

Focus on eating foods that are organic and rich in antioxidants.  Try to eat 5 to 7 servings of vegetables and 2 to 3 servings of fruit every day.  Limit intake of sugar and processed foods.

Drink filtered water, avoiding plastics as much as possible. 

Limit intake of alcohol to no more than 2 drinks per week for women and 4 drinks per week for men.

Ensure adequate, quality sleep.  Aim for 7 to 9 hours a night, focusing on good sleep hygiene.

Integrate mindfulness and stress lowering practices every day.

Improve ventilation and air flow and utilize high quality air filters indoors, including home and work.

Nasal Spray for Prevention and Acute Exposure to Airborne Viral Illness

  1. Over the counter Covixyl is now available to help block airborne viruses from adhering to nasal membranes.  This is best used for prevention or within 4 hours of any known/expected airborne viral exposure. Follow instructions on product.
  • Xlear + Biocidin LSF (mix 5 pumps of Biocidin LSF with Xlear nasal spray) This nasal spray is an herbal anti-microbial that helps to kill viruses in the nasal mucosa.  This is best used within 1 to 2 days of any known/expected airborne viral exposure. Use 1 spray each nostril twice daily.

Prevention Supplement Options: (all supplements available in office or in online store)

  1. Orthomune – 2 caps once daily or 1 capsule twice daily (contains vitamin C 600mg, NAC 600 mg, vitamin D 2500 IU, zinc 25mg and Quercitin 250 mg)
  2. Melatonin – 3 to 6 mg daily (Long Acting Melatonin or Quick Dissolve Melatonin)

*** Orthomune and Melatonin are a great combination for viral prevention. If you prefer to take supplements individually instead of a combination product, we recommend the following;

  • Vitamin C – 500 to 1000 mg once to twice daily (Complete Vitamin C)
  • Zinc – 15 to 30 mg daily (Zinc CTW)
  • Quercitin – 200 to 400 mg daily (Allergy Ease)
  • Vitamin D3 – 2000 to 3000 IU per day (K-Force, Vitamin D3, Liquid D3)

Additional options to discuss with your provider include; curcumin (curcumin phytosome or Turmero), NAC, vitamin A, and adaptogenic mushrooms (Transfer Factor Multi Immune)

The following therapeutic options are started at the first signs of illness, positive exposure and/or positive testing.  Please notify your provider so that we can further personalize support.

Therapeutic Supplement Options: (all supplements available in or office or in online store)

  1.  Orthomune – Increase to 2 capsules twice daily (4 capsules contain vitamin C 1200mg, NAC 1200 mg, vitamin D 5000 IU, zinc 50mg and Quercitin 500 mg)
  2. Viracid – 2 capsules twice daily (contains vitamin A, C, B12, zinc, astragulus, Andrographis, echinacea, L-lysine and European elder)
  3. Curcumin – 500 to 1000 mg three times a day with food (Curcumin Phytosome)
  4. Melatonin – 3 to 6 mg at bedtime (Long Acting Melatonin or Quick Dissolve Melatonin)

***The above 4 products are a great combination for therapeutic treatment for the duration of viral illness.  If you prefer individual products, these are listed below.

  • Vitamin C – increase to 1000 mg two to three times a day (Complete Vitamin C)
  • Zinc – increase to 15 to 25 mg twice daily (Zinc CTW)
  • NAC – 500 to 1000 mg twice daily (NAC)
  • Quercitin 400 to 600 mg twice daily (Allergy Ease)
  • Vitamin D3 – 5000 IU per day (K Force, Vitamin D3, Vitamin D3 with K2, liquid vitamin D3)

Yours In Health,

Susan D. Denny, MD, MPH

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Sleep and CBD

Full-spectrum CBD (cannabidiol) is derived from the cannabis plant and contains various compounds, including cannabinoids, terpenes, and trace amounts of tetrahydrocannabinol (THC). While research on the specific effects of CBD on sleep is ongoing, some studies and anecdotal evidence suggest potential benefits for sleep, and full-spectrum CBD may offer additional advantages due to the entourage effect, where different cannabis compounds work together synergistically. Here are some potential benefits of full-spectrum CBD for sleep:

  1. Regulation of Sleep-Wake Cycles: CBD may interact with the endocannabinoid system, which plays a role in regulating sleep-wake cycles. It could potentially help individuals with sleep disorders like insomnia by promoting a more regular sleep pattern.
    • Reference: Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, Cannabinoids, and Sleep: a Review of the Literature. Current Psychiatry Reports, 19(4), 23.
  2. Anxiety and Stress Reduction: Anxiety and stress are common culprits of sleep disturbances. Full-spectrum CBD may have anxiolytic (anxiety-reducing) effects, which could indirectly improve sleep by calming the mind.
    • Reference: Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente Journal, 23, 18-041.
  1. Pain Relief: Full-spectrum CBD has anti-inflammatory properties that may alleviate chronic pain conditions. Improved pain management can lead to better sleep quality for individuals who suffer from pain-related sleep disturbances.
    • Reference: Russo, E. B. (2008). Cannabinoids in the Management of Difficult to Treat Pain. Therapeutics and Clinical Risk Management, 4(1), 245–259.
  1. Relaxation and Sedation: Some terpenes found in full-spectrum CBD, such as myrcene, have sedative properties. These compounds, in combination with CBD, may promote relaxation and sedation, making it easier to fall asleep.
    • Reference: Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364.
  1. Reduced Nightmares: For individuals suffering from nightmares or post-traumatic stress disorder (PTSD), full-spectrum CBD may help reduce the occurrence of distressing dreams.
    • Reference: Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics, 12(4), 825–836.

Remember – just because a company advertises ‘full-spectrum CBD’ does not mean that it’s what we are discussing here. It’s similar to the caution you need when buying eggs, and you see ‘cage-free’ or ‘free-range.’ Thanks to clever and deceptive marketing strategies, those phrases do not indicate that the chicken was allowed to roam on open pastures eating grass and bugs – that’s exclusive to ‘pasture-raised.’

The CBD market is far more unregulated than an established product like eggs, so it’s essentially the Wild Wild West, and it’s up to you to be informed and do your homework.

What authentic full-spectrum CBD indicates is a product that includes the full range of beneficial cannabinoids, terpenes, and other unique phytonutrients found in hemp. The best way to verify this claim is by looking at the company’s COA, and check to make sure a variety of cannabinoids and terpenes are present.

It’s important to note that while there’s promising research and anecdotal evidence, individual responses to CBD can vary.

It’s advisable to consult with a healthcare professional before starting any new supplement, including CBD, especially if you have underlying medical conditions or are taking other medications.

Always check for recent research and consult with a healthcare provider for personalized guidance.

Your Partner In Health,

Clarissa A. Kussin, ND, FMCHC, ERYT-500

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How does Acupuncture work, and what can it treat?

Katie Depre LAc, LMBT, FABORM, NCCAOM

Though often described as traditional or ancient medicine, research has proven that Acupuncture has its place alongside modern medical practices. Hair-thin needles are placed in precise and therapeutic point locations along meridians. Meridians have been shown to mirror the fascial network of the body. Fascia surrounds all of the organs, muscles, bones, and nerve fibers. These points are located alongside nerve endings and blood vessels, thereby directly influencing blood flow and sensory nerves in the area (2,3). Functional brain imaging has shown changes in the brain when these points are needled (1). Since the brain controls the systems of the body (hormones, blood flow, stress responses, organ function, reproduction, etc.), influencing the brain and nervous system with Acupuncture will impact our health. Treatment encourages the body’s own systems of balance, commonly known as homeostasis.

The National Center for Complementary and Integrative Health outlines many of the researched treatable conditions (4); these include: pain management, osteoarthritis, sciatica, fibromyalgia, cancer pain, irritable bowel syndrome, asthma, depression, allergies, infertility, and menopause symptoms. Though more chronic conditions will require a series of treatment for complete resolution, I have personally witnessed immediate relief from insomnia, digestive complaints, anxiety, and pain in my clinic.  Especially because it is a non-pharmaceutical approach, many patients search out Acupuncture for treatment to acute and chronic conditions.

As a Fellow of the Acupuncture and Traditional Chinese Medicine Board of Reproductive Medicine, FABORM, I treat many patients with their fertility goals. By regulating the menses, we can prepare the body for pregnancy. Fertility work is best done weekly for three months prior to conception, as it takes three months for the egg to develop in the ovaries. During times of sympathetic stress (the flight or fight response), blood is shunted away from the ovaries and uterus. This can negatively impact egg quality and the thickness of the uterine lining.  By encouraging blood flow to these reproductive organs, switching the nervous system into a parasympathetic state (rest, digest, and repair), and regulating the Hypothalamic-Pituitary-Ovarian Axis, we set the body up for success.

For patients undergoing IVF, the Paulus Protocol is utilized. This is a series of points done before and after an embryo transfer. “Clinical pregnancies were documented in 34 of 80 patients (42.5%) in the acupuncture group, whereas the pregnancy rate was only 26.3% (21 out of 80 patients) in the control group (5).”

Please reach out today if you have specific questions on how Acupuncture can help you realize your health goals!

Warmly,

Katie Depre LAc, LMBT, FABORM, NCCAOM

Sacred-sea.com

(919) 808-2638

  1. Huang W, Pach D, Napadow V, Park K, Long X, Neumann J, Maeda Y, Nierhaus T, Liang F, Witt CM. Characterizing acupuncture stimuli using brain imaging with FMRI–a systematic review and meta-analysis of the literature. PLoS One. 2012;7(4):e32960. doi: 10.1371/journal.pone.0032960. Epub 2012 Apr 9. PMID: 22496739; PMCID: PMC3322129.
  2. Langevin HM, Yandow JA. Relationship of acupuncture points and meridians to connective tissue planes. Anat Rec. 2002 Dec 15;269(6):257-65. doi: 10.1002/ar.10185. PMID: 12467083.
  3. Bai Y, Wang J, Wu JP, Dai JX, Sha O, Tai Wai Yew D, Yuan L, Liang QN. Review of evidence suggesting that the fascia network could be the anatomical basis for acupoints and meridians in the human body. Evid Based Complement Alternat Med. 2011;2011:260510. doi: 10.1155/2011/260510. Epub 2011 Apr 26. PMID: 21584283; PMCID: PMC3092510.
  4. Acupuncture: What You Need to Know. National Center for Complementary and Integrative Health. (2022, October). https://www.nccih.nih.gov/health/acupuncture-what-you-need-to-know
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What Exactly Is Applied Kinesiology?

Richard A. Laviano, DC, ND, FSBCT(c)



My doctor has recommended applied kinesiology to rebalance my vagus nerve.
Sounds like voodoo to me…. What exactly is applied kinesiology?

The importance of the vagus nerve for so many of our bodily function has been proven again and again in multiple medical studies. The vagus nerve runs from your brainstem down to your intestinal tract and is the ringmaster of your autonomic nervous system, all things “rest and digest”. When the vagus nerve is out of balance, it has the potential to create widespread dysfunction from intestinal motility (think small intestinal bacterial overgrowth) to quick “fight or flight” reactivity, anxiety, and even panic attacks.  A simple PubMed search of vagus nerve pops up34,789 results! We at CTW have come to rely on the finely tuned skills of practitioners expert in using modalities to rebalance the vagus. One of the most powerful, only in very experienced hands, is applied kinesiology (AK). Dr Rick Laviano of Falls Chiropractic and Injury in Raleigh explains below the role of AK.

Applied Kinesiology (AK) is a neurological rehabilitation therapy. At the International College of Applied Kinesiology in 2005 (1) Dr. Walter Schmitt eloquently presented a model that thoroughly explains it. He explains AK as an assessment and therapy that positively affects neurological function. We quote it here and explain it more simply below.

AK is a series of sensory receptor based diagnostic challenges followed by monitoring of manual muscle testing outcomes. All AK techniques are about creating sensory receptor stimulation that results in a net effect of excitation and inhibition leading to more optimal neurological function. These positive changes can be observed through somatic windows by changes toward normal in muscle facilitation and inhibition(muscle balance, range of motion, deep tendon reflexes) and through various autonomic windows that can also be monitored (pupil light response, blood pressure, heart rate, etc.) (pg. 1)

AK uses muscle tests as well as other neurological tests to assess the state of your nervous system. When there is poor neurological function discovered, the doctor tries his or her best to find the neurological therapy that will improve it. For example, the brainstem (area of the brain just above your neck), controls most of the things in your abdominal cavity subconsciously like your heartrate, blood pressure, gut motility, gut valves, and liver detox. We can see how healthy the brainstem is by looking at reflexes that live there, like how fast your pupils react to a shining light, or how your jaw moves, or how your balance is, or how your blood pressure compares from one side to another (2,4).

A physician trained in AK will use these nerdy tools to pinpoint what part of the nervous system may be dormant or over-excited. Then they will wake it up or calm it down through a targeted therapy such as rubbing, tapping, stretching, manipulation, eye movements, muscle/fascial work etc. AK specialists can be considered your body electricians! The ultimate goal is to improve function in the nervous system to thus improve total body health and wellness.

Since the nervous system controls every function in our bodies, there have been many types of cases Applied Kinesiologists have seen over the years. Cases that are often seen include gut/microbiome issues. It is important that these patients understand that the gut microbiome is STRONGLY influenced by the state of their gut nervous system. Improving the integrity of the nervous system in these patients can greatly improve their quality of life.

Another point worth mentioning regarding gut issues includes the trigeminal nerves. The largest cranial nerve in our brain is the trigeminal nerve. This nerve coordinates information regarding the teeth, jaw, head, and even your posture (3)!This nerve integrates (strongly connects) with the vestibular, ocular, and cerebellar reflexes that affect the health of the brainstem, even the health of the vagus nerve. By keeping the trigeminal nerve and its connections in the brainstem healthy, vagal tone is optimal! In treating gut problems, the priority is making sure that trigeminal, head, eyes, and balance organs are in tune with one another for the health of the autonomic nervous system including the vagus nerve and ultimately the gut.


References:
1.      Schmitt, Walter H., The Neurological Rationale for a Comprehensive Clinical Protocol Using Applied Kinesiology Techniques. Proceedings of the I.C.A.K. – U.S.A. Annual Meeting, Volume 1,2005-2006. p. 157-191.
2.      Monaco, A., Cattaneo, R., Mesin, L., Ciarrocchi,I., Sgolastra, F., & Pietropaoli, D. (2012). Dysregulation of the autonomous nervous system in patients with temporomandibular disorder: a pupillometric study.
3.      Cuccia, A., & Caradonna, C. (2009). The relationship between the stomatognathic system and body posture. Clinics, 64(1),61-66.
4.      Applied Kinesiology Synopsis: David S. Walther. 1988.


Your Partners In Health,
Richard A. Laviano, DC, ND, FSBCT(c) and Ana Dávila, DC Falls Chiropractic and Injury, Raleigh NC

Frances T Meredith, MD Carolina Total Wellness
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Metformin Beyond Diabetes: Exploring Longevity Benefits

Susan D. Denny, MD, MPH

Welcome to this month’s Functional Medicine newsletter, where we delve into the fascinating topic of Metformin, a medication commonly used for diabetes management, and its potential benefits for longevity. While Metformin has long been recognized as an effective treatment for diabetes, recent research suggests that it may have broader implications for promoting overall health and extending lifespan. Join us as we explore the scientific evidence and discuss the exciting possibilities surrounding Metformin’s role in longevity.

Metformin and Diabetes Management

Metformin is a medication primarily used to manage type 2 diabetes. It works by reducing glucose production in the liver and increasing insulin sensitivity, leading to improved blood sugar control. However, emerging studies indicate that Metformin’s benefits extend far beyond diabetes management alone.

Metformin and Longevity Research

  1. Metformin and Aging Markers: Numerous studies have explored the effects of Metformin on various markers of aging, including cellular senescence, inflammation, and oxidative stress. Research suggests that Metformin may have anti-aging properties by modulating these processes and promoting healthier cellular function.
  2. Metformin and Lifespan Extension: Animal studies have demonstrated promising results regarding Metformin’s potential to extend lifespan. Researchers have observed increased lifespan in various organisms, including worms, flies, and mice, when treated with Metformin. While human studies are still ongoing, these findings offer intriguing insights into the possibility of Metformin as an anti-aging intervention.
  3. Metformin and Age-Related Diseases: Metformin’s potential to mitigate age-related diseases, such as cardiovascular disease, cancer, and neurodegenerative disorders, has been a subject of interest. Research suggests that Metformin may exert protective effects on these conditions by influencing key pathways involved in aging and disease development.
  1. References and Further Reading:
    1. Barzilai, N., et al. (2016). Metformin as a Tool to Target Aging. Cell Metabolism, 23(6), 1060-1065.
    2. Martens, C. R., et al. (2018). Metformin as a Tool to Target Aging. Cell Metabolism, 27(4), 758-775.
    3. Hsu, C. C., et al. (2018). Metformin Use and Risk of Cancer in Patients with Type 2 Diabetes: A Nationwide Cohort Study. The Oncologist, 23(7), 859-865.
    4. Foretz, M., et al. (2014). Metformin: From Mechanisms of Action to Therapies. Cell Metabolism, 20(6), 953-966.

We encourage you to explore these references to gain a deeper understanding of the research surrounding Metformin’s potential benefits for longevity and age-related diseases.

Consulting a Healthcare Professional

It is important to note that while Metformin shows promise in longevity research, its use beyond diabetes management is still being investigated. Before considering Metformin or any other interventions for longevity purposes, it is crucial to consult with a healthcare professional who can assess your individual circumstances and provide guidance based on the latest scientific evidence.

Remember, longevity is a multifaceted topic, and adopting a comprehensive approach to healthy living, including balanced nutrition, regular physical activity, stress management, and maintaining a supportive social network, is key to promoting overall well-being and healthy aging.

Wishing you a vibrant and resilient journey towards optimal health and longevity!

Yours In Health,

Susan D. Denny, MD, MPH

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Get Ready For Fall Allergies

Allergies don’t only crop up in the spring. The persistent sniffles, clogged nose, itchy eyes and sneezing also happen in the fall — and, experts say, they are getting more common, and more intense.

Don’t Wait For Fall Allergy Symptoms!

“What a lot of people don’t realize is that the allergy seasons have almost doubled in length and gotten more intense because of climate change,” said Kenneth Mendez, the president and chief executive of the Asthma and Allergy Foundation of America. Higher carbon dioxide emissions spur plants to release larger amounts of pollen, he said. “That’s why allergies are feeling a lot worse.”

Common Fall Allergens

The most common culprit for fall allergies is ragweed, a plant that grows wild almost everywhere, but especially on the East Coast and in the Midwest. Ragweed blooms and releases pollen from August to November. In many areas of the country, ragweed pollen levels are highest in early to mid-September.

Other plants that trigger fall allergies include:

· Burning bush

· Cocklebur

· Lamb’s-quarters

· Pigweed

· Sagebrush and mug wort · Tumbleweed and Russian thistle

Allergy Drops at Carolina Total Wellness

Carolina Total Wellness offers effective allergy treatment for both indoor and outdoor allergies through sublingual immunotherapy drops formulated just for you to safely and conveniently treat the cause of your allergies.

How Allergy Drops Work

Sublingual immunotherapy, also called allergy drops, works similar to allergy shots by gradually helping your body build tolerance to the substance(s) causing your allergies. The difference is that the antigen is placed under your tongue in a liquid drop form instead of an injection.

What kind of allergies can be treated with allergy drops?

One of the benefits of sublingual immunotherapy is that it can treat a broad range of allergies, including those caused by:

· Dust mites

· Mold

· Animals

· Foods

· Seasonal pollens such as grass, trees, ragweed, and mountain cedar, etc.

Who should take Allergy Drops?

Anyone interested in treating the cause of their allergic disease, instead of just temporarily managing symptoms, can consider allergy drops.

· Infants and children*

· Asthmatics

· People with highly sensitive conditions including EoE

· Those who don’t like needles

· Those with chronic conditions including sinusitis and eczema

· Those with food and mold allergies

· Those with multiple allergies including dust mites, pollen, foods, and animals

* Allergy drops have proven especially helpful for children with eczema and recurrent ear infections, which often have underlying allergic causes. Research shows that many children with untreated eczema and allergies often develop asthma and other chronic conditions later in life, so treating them early can have life-long benefits and may prevent development of other allergies and asthma.

What are the advantages to Allergy Drops?

In addition to being a viable option for people of all ages and conditions, there are more advantages:

Lower cost, fewer clinic visits. Compared to shots and many medications, allergy drops typically cost less over time. Most patients receiving allergy drops need only a few clinic visits the first year, and then once every 6-12 months thereafter until visits are no longer needed. That can also mean a lot less time away from work or school.

More convenient. You can take allergy drops at home or wherever you are, making it much easier to stay with your treatment.

Less medication. Our patients report, and research confirms, that they typically need less medication to control symptoms after beginning allergy drops.

Enjoy healthier days. The end benefit of taking drops consistently? Feeling better, more productive and better able to enjoy life and activities that allergies once made it hard to enjoy.

INITIAL ADULT AND PEDIATRIC PATIENT ALLERGY DROPS VISIT: $300

Please allow 45 minutes for your initial visit which will include consultation with your physician or physician assistant, physical exam and discussion of allergy testing. Skin prick testing will be performed at this visit and results and interpretation will be discussed. Prescription will be provided for allergy drops and we will review how to administer these at home.

FOLLOW UP ALLERGY DROPS VISIT: $85

Please allow 15 minutes for your follow up allergy visits. This will include review of your allergy symptoms and immunotherapy plan of treatment as well as new 3-month prescription for allergy drops. Follow up visits are recommended every 3 months for the first year and then every 6 to 12 months for the subsequent 2 to 4 years, depending on your response to treatment.

FOLLOW UP ALLERGY SKIN PRICK TESTING: $125

We recommend follow up skin prick testing for environmental allergies every 12 months to assess progress of immunotherapy and adjust your prescription allergy drops as needed.

To schedule, please call us at 919-999-0831

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Homemade Paleo Ice Cream Delights – Strawberry, Peach, And Honey Lavender Flavors

Dear Ice Cream Lovers,

Get ready to indulge in the delightful world of homemade Paleo ice cream! With summer in full swing, what better way to beat the heat than with these three tantalizing flavors: Strawberry, Peach, and Honey Lavender. Whether you follow a Paleo lifestyle or simply enjoy natural, wholesome treats, these recipes are sure to satisfy your sweet cravings. Let’s dive in and discover how to make these delicious frozen delights right in the comfort of your own kitchen!

1. Strawberry Paleo Ice Cream:

Ingredients:

  • 2 cups frozen strawberries
  • 1 can (13.5 oz) full-fat coconut milk
  • 1/4 cup honey or maple syrup (adjust to taste)
  • 1 teaspoon pure vanilla extract

Instructions:

  1. In a blender or food processor, combine the frozen strawberries, coconut milk, honey or maple syrup, and vanilla extract.
  2. Blend until smooth and creamy, ensuring all ingredients are well combined.
  3. Pour the mixture into an ice cream maker and churn according to the manufacturer’s instructions.
  4. Transfer the churned ice cream into an airtight container and freeze for at least 2 hours or until firm.
  5. Serve the strawberry Paleo ice cream in bowls or cones and enjoy the fruity goodness!

2. Peach Paleo Ice Cream:

Ingredients:

  • 2 cups frozen peaches
  • 1 can (13.5 oz) full-fat coconut milk
  • 1/4 cup honey or maple syrup (adjust to taste)
  • 1 tablespoon fresh lemon juice

Instructions:

  1. In a blender or food processor, combine the frozen peaches, coconut milk, honey or maple syrup, and fresh lemon juice.
  2. Blend until smooth and creamy, ensuring all ingredients are well combined.
  3. Pour the mixture into an ice cream maker and churn according to the manufacturer’s instructions.
  4. Transfer the churned ice cream into an airtight container and freeze for at least 2 hours or until firm.
  5. Scoop the peach Paleo ice cream into bowls or cones and savor the natural sweetness of summer’s favorite fruit!

3. Honey Lavender Paleo Ice Cream:

Ingredients:

  • 1 can (13.5 oz) full-fat coconut milk
  • 1/4 cup honey or maple syrup (adjust to taste)
  • 1 tablespoon dried lavender buds (culinary grade)
  • 1 teaspoon pure vanilla extract

Instructions:

  1. In a saucepan, combine the coconut milk, honey or maple syrup, and dried lavender buds.
  2. Heat the mixture over low heat, stirring occasionally, for about 5 minutes to infuse the flavors.
  3. Remove from heat and let it cool to room temperature.
  4. Strain the mixture to remove the lavender buds and transfer the infused coconut milk into a bowl.
  5. Stir in the vanilla extract, ensuring it is well incorporated.
  6. Pour the mixture into an ice cream maker and churn according to the manufacturer’s instructions.
  7. Transfer the churned ice cream into an airtight container and freeze for at least 2 hours or until firm.
  8. Serve the honey lavender Paleo ice cream in elegant bowls or cones, savoring the delicate floral notes and subtle sweetness.

Enjoy Your Homemade Paleo Ice Cream Creations!

These refreshing and guilt-free ice creams are perfect for hot summer days or any time you crave a chilly treat. Experiment with different toppings or get creative by combining flavors. The possibilities are endless!

Remember to store any leftovers in the freezer, and if the ice cream becomes too firm, let it sit at room temperature for a few moments.

Your Partner In Health,

Clarissa A. Kussin, ND, FMCHC, ERYT-500

Functional Medicine

Functional medicine is a science-based health care approach to assess, prevent and treat complex chronic disease.

Answers to frequently asked questions provided by Carolina Total WellnessLearn More

Allergy Testing & Drops

After a brief allergy test, you can begin sublingual immunotherapy (SLIT), or allergy drops under the tongue. No more allergy shots!

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About Your Visit

Learn how to prepare for your visit and what to expect at your initial consultation and at your follow-up visits with our office.

What to expect at your appointment with Carolina Total WellnessLearn More
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