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Part II –  Low SIgA And How Do We Treat

Shane Hemphill, MD

Part II –  Low SIgA And How Do We Treat

So your functional medicine provider ordered a Comprehensive Stool Analysis and your SIgA levels are found to be low. What is your next step? The answer is going to vary from person to person, but the ultimate answer is in finding the root cause.

This may include evaluating for and removing a food sensitivity, mold sensitivity, or infection that has over time depleted the immune response.

Once we have eradicated our offending agent we need to look at ways to improve our SIgA levels.

As a general rule the first step is to use an anti-inflammatory diet such as a Mediterranean diet. This is rich in fruits, vegetables, nuts, legumes, olive oil, and fish and low in red meat and saturated fats. One can also eliminate fried foods, processed foods, sugary snacks and soda.

More specific treatments Include:

A diet rich in Polyphenols such as cacao, green tea, and grapeseed extract which have shown to increase SIgA levels.

Saccharomyces Boulardii – This probiotic yeast has been shown to raise SIgA levels while also being very effective against Clostridium Difficile and Candida Overgrowth.

Colostrum – an Immunoglobulin secreted in the early stages of breast-feeding. This has shown to stimulate SIgA levels.

Beta Glucans – This is a type of soluble fiber found naturally in a variety of food sources including oats, barley, rye, rice and mushrooms like Reishi and Shiitaki.

Bone Broth – This is made by simmering the bones and the connective tissue of animals. This forms a stock for making soups, sauces and gravies. Depending on which part you use it contains vitamins,  minerals as well as collagen and other amino acids that increase SIgA levels.

Fat Soluble Vitamins – Vitamin A is needed for the transport of SIgA over the mucosal lining. It is suggested that Vitamin A is also involved in the synthesis of other immunoglobulins and has an important influence on our humoral immune system.

Stress Management – Last but not least, Cortisol is the main stress hormone that can decrease SIgA levels. We need to look over your current stressors or perceived levels of stress and then work to reduce them. This can be done through aerobic exercise, yoga, breathing techniques, meditation as well face to face conversations with your friends, family or therapist.

Our functional medicine physicians can help you understand the root cause of low SIgA and design a treatment plan specifically for you, please call our office at 919-999-0831 to get scheduled. 

Your Partner in Health!
Shane Hemphill, MD

New Study Shows Mold Triggers Brain Inflammation

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Landlords dismiss it, friends and family think you’re making it up, and doctors have no idea what you’re talking about — but mold illness is often an unsuspected trigger of chronic health problems. The recent revelation of a string pediatric deaths at a Seattle hospital due to mold in the air system brought national attention to the gravity of mold illness.

Newer construction methods and materials, water damage that was not properly addressed, high indoor humidity levels, and genetic susceptibility are all factors that play a role in whether a person becomes sick from mold. Estimates vary, but some research shows up to 85 percent of building inspected had past water damage.

A new study found that people affected by mold illness experienced:

  • Brain inflammation in the hippocampus, the area of the brain that governs memory, learning, and the sleep-wake cycle.
  • Decreased neurogenesis, or the formation of new brain cells.
  • Impaired memory.
  • Increased sensitivity to pain.
  • Increased anxiety.

The study also noted that the mold spore alone is not necessary to trigger mold reactions and mold illness. We’ve long known that mycotoxins, toxic compounds produced by mold spores small enough to pass through most materials, are the primary trigger in mold illness.

The study also found that mold spore skeletal elements and other mold metabolites also cause symptoms of mold illness.

Researchers link mold-triggered immune activation with these symptoms in the brain and the body, concluding that mold causes symptoms and illness through its inflammatory effects.

Symptoms of mold illness

Symptoms of mold illness vary from person to person, although mold has been correlated with a significant increase in asthma.

People who live, work, or go to school in moldy buildings complain of pain, fatigue, increased anxiety, depression, and cognitive defects such as memory loss. Researchers say the symptoms are similar to those from bacterial or viral infections, due to the inflammatory cascades mold triggers.

The effects of mold illness on the brain have gone largely dismissed by the standard health care model due to insufficient research on the neurological effects of mold illness.

However, this study demonstrates what people with mold illness already know — it messes with your brain. Hopefully similar studies will follow.

In the study, researchers observed that mice inoculated with mold spores showed increased inflammation in the hippocampus, causing notable losses of memory, increased pain, and more anxious behavior compared to mice inoculated with saline.

Addressing mold illness

If you suspect you suffer from mold illness, a variety of in-home tests can show whether the building has high levels of mold and which kinds. Lab testing can show whether you are dealing with high mold mycotoxin levels and if so, which molds are the culprits.

It’s important to have this information because the type of mold you’re dealing with will help determine the best course of action for recovery.

You must take action to deal with mold illness. Sometimes this can mean dramatic changes, such as moving or leaving a job. If the mold contamination is advanced, it can also mean getting rid of all your belongings. However, without action, the inflammation will continue to ravage your system and progressively damage the brain and body. Mold can also trigger or exacerbate autoimmune diseases such as Hashimoto’s hypothyroidism, multiple sclerosis, vitiligo, and more.

Ask my office how we can help you address possible mold illness.

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