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Managing Hashimoto’s by Supporting T reg Cells

831 supporting t reg cells hashis

When it comes to autoimmune Hashimoto’s hypothyroidism, dampening inflammation and immune attacks on the thyroid is the primary goal. One of the most powerful allies in this quest is to support your regulatory T cells (T reg cells). These are immune cells that do what their name implies — they help regulate the immune system. This means they play a role in either activating or dampening inflammation. The good news is that when it comes to Hashimoto’s, we can do many things to influence the T reg cells to dampen inflammation and quell Hashimoto’s flare ups and attacks so you can have more good days.

Ways to support T reg cells to manage Hashimoto’s

Following are some proven ways we can support our T reg cells to manage Hashimoto’s.

Vitamin D (cholecalciferol). Fat soluble vitamin D is a powerful supporter of the T reg cells, especially at therapeutic doses (around 10,000 IU a day).

Vitamin D is also important because studies show many people with Hashimoto’s have a genetic defect hindering their ability to process vitamin D. Therefore, they need higher amounts of vitamin D to maintain health. This can be the case even if a blood test shows sufficient levels of serum vitamin D. That’s because the defect is at the cellular receptor site, preventing vitamin D from getting into the cells.

Omega 3 fatty acids. The EPA and DHA in fish oil support T-reg cells. It’s important to make sure you take enough; it’s estimated 80 percent of the population are deficient in essential fatty acids.

Research shows a healthy dietary intake of supplemental omga-3 is 3,500 mg if you eat 2,000 calories per day.

The average EFA capsule is 1,000 mg. Most people in the US eat between 2,000 to 3,000 calories a day and therefore should take 4 to 6 capsules of fish oil a day. Dietary sources of omega 3 include cold water fish, nuts, and seeds.

Glutathione. Glutathione, also known as the master antioxidant, supports T reg cells and is a powerful support in dampening inflammation and managing Hashimoto’s. Straight glutathione cannot be absorbed well but there are other ways to take it, including reduced glutathione, s-acetyl-glutathione, liposomal glutathione, and glutathione precursors.

Glutathione precursors make glutathione inside the cells and include n-acetyl cysteine, cordyceps, Gotu Kola, milk thistle, and alpha lipoic acid. Don’t be shy to take large amounts of glutathione support to dampen inflammation.

Short chain fatty acids (SCFAs). SCFAs are powerful signaling compounds that influence the health of the body and brain. They are produced by healthy gut bacteria that come from eating a diet abundant in a diverse array of vegetables. The more abundant and diverse your gut bacteria the better your SCFA production.

This helps many functions in your body, including proper T reg cell function and dampening of inflammation and managing Hashimoto’s. You can also take the SCFA butyrate to support your SCFA levels, however, you’ll need to make sure you’re eating plenty of vegetables throughout the day too for this strategy to be effective.

Endorphins. Saving the best for last, did you know a powerful way to support anti-inflammatory function of T reg cells is to experience joy, happiness, love, and playfulness? All of these things produce endorphins, feel good chemicals that reduce inflammation. Methods for increasing endorphins include:

  • Socializing regularly with healthy people
  • Laughter
  • Sex
  • Healthy touch
  • Feeling love
  • Meditation and breath work
  • Massage and other forms of body work
  • Doing something playful regularly
  • Daily expression of gratitude via a journal or verbal affirmation
  • Regular exercise that gives you a “natural high” but doesn’t wear you out

These are some of the ways you can manage your Hashimoto’s hypothyroidism. Ask my office for more information.

Gut Bacteria and the Heart

832 gut bacteria and the heart

Unhealthy gut bacteria are a bigger risk for atherosclerosis, or hardening of the arteries than smoking, cholesterol levels, obesity, or diabetes. Atherosclerosis is the leading cause of heart disease.

That’s because the root cause of heart disease is inflammation. In fact, most modern health disorders are rooted in inflammation, including arthritis, diabetes, obesity, dementia, depression, and inflammatory bowel disease. Cardiovascular disease is no exception.

So where do gut bacteria come in? Researchers have discovered an unhealthy microbiome — the term given to our inner garden of gut bacteria — is pro-inflammatory while a healthy gut microbiome is anti-inflammatory. Unfortunately, Americans have the unhealthiest gut microbiomes studied thus far.

A recent study found that women experiencing hardening of the arteries also showed less gut bacteria diversity while women with healthy arteries showed healthier gut bacteria. A diverse array of gut bacteria is linked with better health.

The study also found that in healthy subjects, diverse and healthy gut bacteria produced more indolepropionic acid (IPA), a neuroprotective antioxidant that also has been shown to lower the risk of diabetes.

The gut microbiome and high blood pressure

It turns out there is more to high blood pressure than reducing your salt intake. Researchers have found high blood pressure, which increases your risk of heart disease and stroke, can also be linked to the gut microbiome.

The key is in a compound called propionate, one of several short-chain fatty acids (SCFAs) produced by healthy gut bacteria. Scientists are learning that SCFAs such as propionate and butyrate are instrumental to the health of the brain and body in many ways, with propionate being specific to the cardiovascular system.

How to foster a heart-healthy gut microbiome

Although taking propionate may help, it won’t do much good if it’s battling a minefield of infectious and inflammatory gut bacteria. Just as healthy gut bacteria produce SCFAs that are good for us, bad bacteria produce the highly inflammatory compound lipopolysaccharide (LPS).

The key to a heart-healthy gut microbiome is to eat about 25–30 grams of fiber a day via a very diverse array of vegetables and modest amounts of fruit (fruits are high in sugar and too much sugar is inflammatory).

It’s the diversity of vegetables that matters most, with research increasingly confirming that a diverse gut microbiome is what lies behind good health and a lower risk of disease.

Switch up the vegetables you eat regularly and shop at world markets unfamiliar to you to try new types of produce. Even a teaspoon of different new veggies each day is enough to help colonize the friendly bacteria that will work to keep your heart healthy.

In this fiber-rich environment, supplementing with SCFAs such as butyrate and propionate can help boost your gut bacteria to produce even more of their own SCFAs.

Additionally, make sure to keep your blood sugar stable by eliminating sugars, sweeteners, and processed carbohydrates, avoid foods that cause an immune reaction in you (for example, gluten and dairy do for many people), avoid toxin chemicals in your foods and body products that can kill good bacteria, and exercise daily — exercise has been shown to positively influence your gut microbiome.

Ask my office for more advice on how to cultivate an optimal gut microbiome and detoxify bad bacteria.

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